As each study has unique requirements, the below publications provide examples of how Sanguine has partnered to recruit, consent donors, and collect samples to fit our client's project needs. In Bame et al., the team needed whole blood from healthy donors and donors diagnosed with MS with no history of B-cell depleting therapies for in vitro preclinical pharmacodynamic readouts. Frikeche et al. used PBMCs collected and isolated by Sanguine from donors with criteria for active disease and specific medications to examine in vitro MOG-CAR Treg as a candidate treatment. These are two example of how our extensive Donor Network and comprehensive medical records, we can achieve your biospecimen needs.