Overview +

All Sanguine study protocols and their resulting samples, which include all Sanguine at-home and apheresis collection programs, are conducted under an Institutional Review Board (IRB). Sanguine operates under an electronic informed consent process which executes 21 CFR part 11 compliant e-signatures, and Sanguine systems interacting with study participant information are HIPAA-compliant.

Sanguine’s human peripheral blood mononuclear cells (PBMCs) are collected from whole blood or leukopak and expertly isolated within one day to maximize viability and functionality. After cells are isolated, washed, and counted, PBMCs are aliquoted and stored using CryoStor® CS10 freezing media. PBMCs include verified disease state diagnosis, donor-reported allergies, and infectious disease history. We offer LeukoLot™ bulk PBMCs isolated from a leukopak, providing up to 2 billion cells from a single donor. You can screen multiple donors before committing to a full- or half-LeukoLot.

Well-characterized PBMCs for hidradenitis suppurativa (HS) research supports studies on chronic skin inflammation, immune dysregulation, and therapeutic development to improve treatment options.

Infectious disease testing requirements differ globally. If you are ordering from outside the U.S., please reach out at to confirm that we can meet your country’s regulatory and documentation needs.